Conditions

Tuberculosis

Overview

Tuberculosis (TB) is a deadly, highly contagious disease cause by the gram positive bacterium Mycobacterium tuberculosis. The history of tuberculosis and humans has been intertwined since ancient times. There is evidence than Neolithic aged, prehistoric humans had contracted TB as early as 7000 years ago. TB can also infect animals.
Tuberculosis Symptoms
Evidence of TB has also been found in bison dating back 18000 years. TB was widespread in antiquity, with evidence of the disease being found in Egyptian mummies, dating back several thousands of years. TB was also known to the ancient Greeks who called the disease phthisis. Until TB was found to be bacterial in origin, the disease was commonly referred to as consumption.

TB has been responsible for millions of deaths throughout history, taking the lives of many famous individuals including the Bronte sisters, Frederic Chopin, George Orwell, Anton Chekhov, John Keats, and Elenore Roosevelt. TB continues to be a threat to this day, even with modern medical advances and treatments.

The German bacteriologist and physicist Robert Koch isolated Mycobacterium tuberculosis, the bacterium that causes TB, in 1882. At the time, despite the efforts of Louis Pasteur and other leading scientists, it was common knowledge that infections happened spontaneously in humans. The idea that bacteria, viruses, or other microscopic organisms could cause disease was incomprehensible for the layman. However, as germ theory gained more proponents, and as medicine has advanced, today that line of thinking has given way to modern theories of infectious disease. Koch was awarded the 1905 Nobel Prize in medicine and physiology.

Alternate Names

Tuberculosis has several alternate names. It’s most common alias is consumption. The term consumption was coined in the 18th and 19th centuries as a way to describe TB’s wasting away effect on the human body. People stricken win the disease were consumed with coughing and fatigue during the disease’s terminal stage, leading to the common name. Tuberculosis infections often leave victims with a pale, ghost-like complexion. Because of this, TB has also been nicknamed the White Plague. In humans, the primary form of TB infection is pulmonary tuberculosis.

Symptoms

In three quarters of the cases of tuberculosis, infection occurs primarily in the lungs. This is called pulmonary tuberculosis. Symptoms include:

  • Productive cough lasting over three weeks
  • Chest pain
  • Coughing up blood or bloody sputum
  • Fever
  • Chills
  • Fatigue
  • Weight Loss
  • Pale appearance
  • Loss of appetite
  • Night sweats

Tuberculosis can also infect other areas outside of the lungs including the bones, blood, and central nervous system.

Causes of Tuberculosis and Means of Infection

Tuberculosis is an airborne disease, meaning that it can spread from person to person by inhaling tiny droplets of mucus and sputum. These droplets get into the air for people it inhale when an infected person coughs, spits, sneezes, or even talks. It has been shown that one sneeze or cough can release tens of thousands of microscopic droplets of bacteria-rich sputum into the air. Infection by the TB bacterium can occur by less than ten of the bacteria, so the potential for widespread infection is tremendous. The incubation period for tuberculosis is between 2-12 weeks. This is the time that it takes for a TB test to detect the disease.

Tuberculosis can lie dormant in a person’s bodies for several years. In one out of ten patients, latent TB can develop into an active TB infection. A person is only contagious if he has an active form of TB infection. Latent TB carriers cannot transmit the TB bacterium to other people. Even though infected with the tuberculosis bacterium, nine tenths of those afflicted will have latent tuberculosis. Out of those 90% of people, 10% will develop active TB in their lifetimes.

When a person inhales aerosol droplets of infected mucus, the infection begins when the bacteria reach the alveoli of the lungs. Infection usually occurs between the upper part of the lower lobe or the lower part of the upper lobe of one of the lungs. Once infection has set in, TB can spread throughout the body through the lymphatic system and blood stream.

Bacterium

Tuberculosis bacterium can cause the immune system to produce what is called a granulomatous inflammatory response. Put simply, this is method employed by a person’s immune system in which it attempts to build a wall around pathogens it is unable to destroy. This is done in hopes that isolating the pathogen from the other cells will cause it to die. In the case of tuberculosis, when a TB bacterium is “walled off” it forms a structure called a granuloma. These granulomas can cluster together to form nodules called tubercles or tuberculosis nodules. The TB bacterium can cause necrosis (cell death) in the tubercles, causing tissue damage to the lungs.

Tuberculosis bacteria can also spread through the body via the blood stream and/or the lymphatic system. When it does this, it can produce a systemic infection of the body, including the brain and bones. This is an extremely dangerous form of TB called miliary tuberculosis. Most often, this strikes the immune suppressed, elderly, and children.

Patients with tuberculosis can go through periods where the disease changes in its severity, shifting between good and bad periods for the patient. In this time, tissues can be destroyed and repaired although scarring occurs.

Risk Factors

A condition called silicosis may increase the risk of tuberculosis infection by a factor of 30 in people suffering from the affliction. Silicosis is an occupational hazard disease that is the result of inhaling too much silica. Silica dust is crystalline and rough in texture, which can cause inflammation and scarring in the lungs. Silicosis inhibits the function of white blood cells in the lungs. In a human, when a foreign body is detected by the immune system, specialized white blood cells are released to kill the invading pathogens.

Another risk factor for being infected with tuberculosis is being on dialysis. Because people on dialysis are generally in worse health than the rest of the population and because their immune systems may be compromised due to this weakened state, the risk of developing a TB infection increases by 10-25 times that of the normal population.

Having a low body weight in relation to height may increase the risk of becoming infected by TB by a factor of 2 to 3.

Another group that is at a higher risk of developing TB than the general population is diabetics. Diabetes, especially in patients with poorly controlled glucose and insulin levels can elevate the chances of getting a TB infection by 2-4 times.

Certain drugs may also put a person at increased risk for being infected with TB. Immunosuppressants and some rheumatoid arthritis drugs may increase the chance of infection.

Tests and Diagnosis

When confirming a case of tuberculosis, several steps are taken to develop an accurate diagnosis because many of the symptoms of TB resemble those of less serious diseases.

When a patient first presents with symptoms consistent with a diagnosis of tuberculosis, a physician will take a detailed medical history of the patient. This allows the doctor to gain an overall picture of the person’s health. A patient’s medical history may include known instances of exposure to TB, prior TB infections, and any medical conditions like silicosis that may increase the chances of being infected by tuberculosis.
Treating TB
Although a physician may suspect tuberculosis from the symptoms, it is impossible to make an absolute conclusion without bacterial cultures being taken. Sputum cultures are taken and smeared onto growth medium in Petri dishes. The samples are allowed to incubate for a period of time, during which the bacteria can grow and multiply. After several hours or days, the dishes are examined under a microscope by a pathologist who can determine what bacteria are present in the sample. If tuberculosis bacteria are found, that is a definitive sign that the patient is indeed infected with TB and may have an active form of it.

Chest X-rays

Chest X-rays are often helpful to chart the progression of tuberculosis but not enough on their own to make a definitive diagnosis. When an abnormal chest X-ray is obtained from a patient, a radiologist may look at the film and find indications that suggest an active case of tuberculosis. These include:

1. Patches that may indicate foreign matter

2. Holes without irregular margins

3. Nodules with hazy edges

4. Fluid

5. Enlarged lymph nodes

Evidence of inactive tuberculosis can also be found on a chest X-ray. These signs include:

1. Scar tissue

2. Nodules with distinct edges

Tuberculosis Skin Tests

The Mantoux test is a skin test that is used for screening for tuberculosis. In this test, a patient is injected with a small amount of a protein derived from the TB bacterium called tuberculin. Although the injection of tuberculin into a patient will not cause a tuberculosis infection, the body’s immune system will take action and react to the foreign agent. The test can take 2-3 days before results can be seen. In a negative test, there will be no swelling at the injection site. For a positive result, a small bump ranging in size from 5 to 15 mm will appear at the spot of the injection.

A positive result means that a person has been exposed to TB. The size of the bumps in different groups of people determines a positive result. In immune suppressed persons, a 5 mm bump is enough to be considered a positive result. A 10 mm bump is required for a positive result in person who have been exposed to high risk environments or in those who have chronic diseases that put them at a higher risk of developing TB. Finally, to obtain a positive result in people with no known risk factors for TB, a bump greater or equal to 15 mm is required.

Interferon gamma release assay tests are new blood tests that can detect the presence of TB bacterium. In these tests, a sample of blood is drawn from the patient and mixed with antigens. Antigens are molecules that produce a response from the immune system. The test is based on the fact that white blood cells that are active during the immune response will release a chemical called interferon gamma when exposed to particular antigens — in this case for TB. After a period of 12-16 hours, the amount of interferon gamma is measured to determine whether or not a person is infected.

Treatment Options

Without treatment, tuberculosis has a mortality rate of between 50% and 66%. Treated, the mortality rate for TB drops to 5%. Standard treatment of tuberculosis depends heavily on antibiotic regimens. The TB bacterium is very hardy and poses difficulty for antibiotics to gain entry into its cells. Unlike other bacterial infections, which can take a matter of days to clear with standard antibiotic therapy, tuberculosis treatments require periods of 6-24 months of antibiotic treatment to full rid the body of the bacteria. For active TB, the antibiotics of choice are rifampicin and isoniazid. In latent TB, only isoniazid is required.

The main problem with standard treatment options is the duration of treatment time, over the course of up to 2 years, can lead to patients who become non-compliant. Non-compliant patients are those who do not follow the course of treatment as prescribed and skip doses of antibiotics. A number of reasons may contribute to patient non-compliance including:

  • The size of the pills
  • The fact that some pills must be taken with food
  • Forgetfulness
  • Lack of motivation because the treatment lasts so long
  • Prematurely assuming they are cured

It is very important to maintain a proper regiment when undergoing antibiotic treatment for tuberculosis because TB may not be fully eradicated or antibiotic resistant strains of TB may develop.

In recent years, drug resistant tuberculosis has become a major health issue. Drug resistant tuberculosis is TB that has mutated in such a way that rifampicin and isoniazid are no longer effective. Drug resistance can develop when patients skip doses of their medications. While the medications may kill off most of the bacteria, there are always some that survive the first doses.

When a person skips doses, these hardier bacteria survive and multiply. The person may restart the treatment, again killing all but the strongest bacteria. They may stop taking the drugs again, and the cycle repeats until eventually, fully drug resistant bacteria are born. These can be very difficult to treat since they have immunity against the most effective TB antibiotics.

To treat drug resistant TB, other, less effective and less efficient antibiotics may be used, however they may not be enough to stem the attack. In these cases, surgery to remove an infected part of the lung may be the only option.

Prevention

Preventing the spread of tuberculosis can be accomplished by treating those who are infected and those who have come in contact with the infected. Also, proper sanitation techniques such and hand washing, not touching one’s face, and wearing masks in high risks areas can help to prevent infection. A TB vaccine is available for children in high risk areas. Vaccinations of children for TB are common in developing nations that have a high rate of TB infection. Although the vaccine prevents TB in up to 80% of children, it is ineffective in protecting adults from pulmonary tuberculosis which is the most common form found in the world today.

Conclusion

Tuberculosis has been with human kind since antiquity and remains a problem to this day. In fact, tuberculosis is the most widespread disease in the world, infecting 1/3 of the world’s population. With the population of the earth nearing 6 billion people, that means that 2 billion are infected with TB. Most of these cases are latent TB, but active TB will develop in 10% of those infected. Without treatment, TB is often fatal, however, with modern antibiotics, the mortality rate of treated TB is less than 5%.

Many efforts are being made in TB research to create a vaccine that can be used universally to prevent TB in all groups. With any luck, in the near future, tuberculosis may finally be a distant memory with advancements in modern biochemistry and medicine. Until then, it is important to get screened for TB and to recognize its symptoms. Treated early and decisively, TB can be tamed, but waiting too long can lead to a less favorable outcome.

Conditions

Dry Skin

Definition of Dry Skin

The skin is the essential covering for the body, offering physical, thermal and moisture protection against the environment. The skin weighs more than twice the weight of the brain; and during a normal year sheds 1.5 pounds (0.68 kilograms) of dead cells. Alternative names, for the skin, are “dermis” or “dermal.”

There are multiple layers to the skin, the outermost layer is called the “epidermis” from the Greek prefix, “epi” which means “upon.” It is also referred to as the “stratum corneum.” Just like a garden, the skin consists of an outer layer of dead or peeling skin, that has the same function as mulch, deflecting harmful ultraviolet rays, drastic temperature changes, retains moisture and provides water-proofing. When this outer layer is damaged, it can lead to dry skin: “Xerosis Cutis” or “Xeroderma.”
Causes of Dry Skin
Healthy skin is smooth, pliable and soft, moisturized by natural, lipid oils that are secreted by the sebaceous glands; these prevent evaporation, dehydration, and heat loss. Below the dead skin cells are the living skin cells, which include sweat glands, nerve endings and hair follicles.

Symptoms

When the skin is not properly moisturized due to the malfunctioning of the “stratum corneum,” dry skin is the result. Dry skin starts to shrink, like clothes, leading to cracks and fissures. Extreme conditions include pus oozing and bleeding.

Symptoms of dry skin can include the following:

  • Acne-like bumps
  • Cracking
  • Discolouration
  • Flaking
  • Itchiness (Pruritus)
  • “Parched” look
  • Peeling
  • Powder-like deposits
  • Rash
  • Redness
  • Scaling
  • Tightness
  • Uncomfortable feeling.

A doctor should be called when the following serious conditions occur with the dry skin:

  • Bleeding
  • Oozing pus
  • Severe cracks.

Causes

Specific

Most normal, healthy, skin is protected by a thin, layer of oil to prevent damage to more sensitive areas below. The most common specific causes of dry skin are harsh, cleaning chemicals (soap and detergents) and environmental factors (humidity, sun, temperature, and wind.) Many chemicals in common cleaning products strip “lipids” (oils, fats and wax molecules) from the top skin layer, leaving more sensitive layers underneath vulnerable. Every day, the weather can cause dry skin; this can be counteracted with normal lubrication via oil, lotion and cream.

Specific causes of dry skin are numerous, including the following:

  • Alcohol-based cleansers
  • Dehydration
  • Dry heat
  • Excessive washing
  • Harsh chemical cleansers
  • Heating systems – Fireplaces, furnaces, and heaters
  • Malnutrition, a diet provides essential nutrients for skin growth, repair and recovery
  • Medication treatments (like Antihistamines, Antispasmodics, Diuretics, and Retinoids)
  • Sand, sun and wind
  • Temporary, seasonal condition caused by low air humidity.

B.) General Categories

The following names some general dry skin causes:

  • Diabetes – Poor glucose production leads to moisture evaporation
  • Hodgkin’s Disease – Red, itchy patches
  • Ringworm infection – Red, scaly, rash patches caused by fungus
  • Sjogren’s Syndrome – Increases sensitivity to sunlight leading to burnt skin
  • Thyroid conditions – Skin colour may change.

4.) Risk Factors

All people can develop dry skin, but some risk factors lead to more recurring dry skin.

Risk factors for dry skin include the following:

  • Aging
  • Babies, children and women have more sensitive skin
  • Dry, dusty summer beach conditions
  • Dry, winter climate
  • Genetics
  • Hormone changes
  • Living in unhygienic conditions
  • Poor diet – Vitamins A, B, C, E and K are good for skin
  • Rough clothing fabrics
  • Soking.

Prevention Tips

Moisture levels change every day in the skin, thus, it is wise to have lubricating oils, lotions and creams in constant supply. Especially, after bathing it is wise to use lubrication to re-moisturize the body after soaps and body cleansers dry out the skin. People who are concerned with dry skin should avoid high-alkaline, high-alcohol soaps.

People with more sensitive skin should try milder soaps and body washes, with ultra-moisturizing qualities, like Dove, Neutrogena or Oil of Olay, to see which ones have the best chemical pH balance for helping them retain skin moisture. Saunas and warm moderate temperature bathing can help keep skin pores remain clean and healthy.

Moisturizers, like Eucerin and Cetaphil, are good at helping keep water inside the skin after bathing. Apply baby oil when skin is still moist; moisturizing lotion and an extra layer of cleansing cream can help skin during times when dehydration is an increased threat.

It is wise to keep lotion on-hand always, in case, conditions dry skin out, then you can replenish your skin’s moisture quickly. Dry skin can be a vicious cycle – once skin gets dry, it starts to crack, open skin leads to bleeding or infection – which makes it even more difficult to treat. During harsh seasons, it may be wise to control bathing; constant hand washing quickly strips the body of essential oils.

Avoid drying environmental conditions, like the sun’s ultra-violet (UV) rays. Experts have carefully studied the sun’s light, dividing its ultra-violet rays into smaller segments, like UVA, UVB and UVC:

  • UVA – Remains the same strength year-round, can cut through outer epidermis to damage underlying dermis
  • UVB – Intensity changes based on hemisphere and season, most sunblocks protect against
  • UVC – Most dangerous, usually are absorbed by ozone layer.

Using sunblock (sunscreen) with a Sun Protection Factor (SPF) over 15 can help protect against dangerous ultraviolet rays.

Laundry and Detergents

Using powerful detergent, chlorine chemical cleaning products can also dry skin quickly. Eco-friendly, neutral-pH products are best for washing; using protective, latex, rubber gloves while cleaning with harsh chemicals can also protect skin from dehydration. People should apply extra layers of lubrication before-and-after cleaning.

Those who suffer from dry skin must make sure that their towels, clothing and environment are particularly clean. A rough wash cloth can accumulate mold, mildew or dirt that might dry out the skin. Keeping the cleaning environment clean can help prevent dry skin.

Proper nutrition provides the basic vitamins, nutrients and minerals for nourishing the skin: Vitamins A, B, C, E and K are great for the skin. A good multivitamin can help prevent dry skin. Dietary supplements, like Omega-3, can help dry skin. Foods that are great for the skin include: cantaloupe, carrots, cheese, garlic, milk, nuts, onions, peaches, salmon, sardines, seeds, tuna and vegetables, yogurt, walnuts, and whole grains. Pure, extra virgin oils – coconut, olive and safflower – can also help prevent skin damage.

Stop engaging in negative behaviours that dry out the skin, like smoking, to prevent dry skin. Natural fibres, like cotton, can help the skin breathe better than artificial fabrics. A humidifier can also keep moisture in the air.

Test and Diagnosis Considerations

Testing

The most common tests for dry skin include 1.) “Skin Culture Swab” of the affected area searching for bacteria, fungus or yeast, or 2.) “Skin Lesion Biopsy” looking for serious conditions, like Eczema. These usually are conducted by a dermatologist who will also consider the patient’s family medical history and other risk factors.

Diagnosis Factors

Dermatologists will ask a series of questions in order to gather information that might reveal the source of your dry skin:

  • When did you first notice your dry skin?
  • Do you have a family history of dry skin?
  • Which parts of your body are dry?
  • What are your bathing habits?
  • Are you taking any medication?
  • Do you smoke?

Dry Skin Maladies

Different parts of the body can experience dry skin – face, ears, nose, hands and legs – that require different responses.

The following are the most serious dry skin maladies:

Atopic Dermatitis (Eczema) – This is a common dry skin condition leading to itchy, scales that could be fish-like and could be caused by food allergens. This occurs when skin cells fail to shed away properly; instead, the dry skin cells build up in polygonal shapes. These scales may turn different colours ranging from white to brown. Flaking, fissures and bleeding may occur. Lesions are also possible: “dry, scaly lesions,” “thick, chronic lesions,” and “weeping lesions.”

  • Asteatotic Eczema (Eczema Craquele or Xerosis) is the abnormal drying of skin that may lead to cracked or fissured patches.
  • Athlete’s Foot is a fungal infection of the foot that leads to dry flaking.
  • Dermatitis is reddened round, scaly, skin.
  • Ichthyosis Vulgaris sufferers experience fish-like scales on their skin.
  • Keratosis Pilaris leads to small, hard, acne-like bumps within hair follicles. This condition may have some genetic characteristics.
  • Nummular Eczema is allergy-related, with red, itchy, scaly lesions that have yellow crusts or pus due to oozing.
  • Psoriasis is a chronic, recurring condition with red, scaly skin that might crack, ooze or bleed.

Treatment Options

Herbal and Home Remedies

The most basic of all cures for dry skin includes drinking plenty of water. There are many homemade remedies for maintaining skin moisture, including the mixture of organic granulated sugar, honey and extra virgin olive oil. Another skin treatment mixture is made of eggs, honey, olive oil and rose water.

Natural oils – almond, avocado, bitter orange, lemon and lime – are good for treating dry skin. Crisco vegetable shortening can be used to treat dry skin.

Vitamins and mineral supplements can assist in curing dry skin:

  • Gotu Kola
  • Green tea
  • Honey
  • Hyaluronic Acid
  • Trypsin.

A milk bath is also a common home remedy to moisturize skin.

Holistic herbs for curing dry skin include these:

  • Borage
  • Calendula flower
  • Chamomille tea
  • Coltsfoot
  • Comfrey plant
  • Dandelion tea
  • Geranium
  • Fennel
  • Hyssop
  • Lavendar oil
  • Oat extract
  • Patchouli
  • Peppermint tea
  • Rose
  • Sandlewood.

Pharmaceutical

External creamy, moisturizing cleansers with glycerin or petrolatum, such as, Aveeno Daily Moisturizing Body Wash or Oil of Olay Sensitive Skin Soap are good for treating dry skin.

Follow this step-by-step procedure for using moisturizers after bathing:

1.) Moisten dry skin
2.) Let water soak in
3.) Pat water to retain moisture
4.) Add bath oils,
5.) Cover body with lotions or creams that aren’t washed off easily.

High moisturizing oils include Neutrogena Light Sesame Seed Oil, Hermal Body Oil, and Alpha-Keri Oil. Wonderful dry skin lotion moisturizers include Lubriderm, Keri and Nutriplus. Skin cleansers, like Cetaphil Lotion, Oilatum-AD and Aquanil are also effective. Great, hypoallergenic, cream, moisturizers for dry skin include Carmol, Cetaphil, Nivea, and Nutraderm.

Additional Ointments

Vaseline Petroleum Jelly is a good moisturizing ointment. Oral Antihistimines that might relieve dry skin include Diphenhydramine (Benadryl), Hydroxyzine (Atarax), and Cetirizine (Zyrtec). Dry skin can lead to annoying itching; Anti-itch products containing Praxomine, Menthol, Camphor, Pramosone, Hydrocortisone, Triamcinolone, Clobetasol are safe to use for treatment.
Treating Dry Sking
A dermatologist might prescribe the following products for Dermatitis: an Immunomodulator, like Tacrolimus or Pimecrolimus. Antibiotics might be needed to treat bacterial infection from serious oozing lesions.

Common drugs for treating dry skin:

  • Accutane
  • Bactroban
  • Benzoyl Peroxide
  • Clobetasol
  • Elidel
  • Hydrocortisone
  • Metrogel
  • Nizoral.
  • When using a combination of Cortisone and moisturizer as a treatment; apply Cortisone first.

Specific Treatments

Eczema can be treated with moisturizing anti-itch oils, lotions, creams, topical Corticosteroids, along with a wet dressing for “weeping lesions.” “Thick, chronic lesions” can be treated with tar-based compounds and anti-inflammatory medicines to lubricate and soften the skin. Antihistamines might attack the allergic problems underlying the symptoms. Dermatologists might prescribe oral Corticosteroids to reduce inflammation or Topical Immunomodulators (TIMs) – Tacrolimus (Protopic) or Pimecrolimus (Elidel) – for hypersensitivity. A cold compress can reduce redness and itchiness.

Keratosis Pilaris has rough patches that can be treated with moisturizing lotions and creams, made of lactic acid, urea, glycolic acid, salicylic acid, and tretonoin, for handling the itchiness. This condition will return if therapy regimen is not continued.

Surgeries

Surgery is an extreme response that isn’t usually used for dry skin problems.

Side effects

Risks

Dry skin that continues as a problem can lead to the following side effects:

  • Bacterial infection
  • Bleeding
  • Cellulitis
  • Discoloration
  • Disfigurement
  • Insomnia
  • Lichenification (roughness)
  • Mental distress
  • Painful cracks
  • Wrinkles.

Efficacy

Most oils, lotions and creams are very effective at treating dry skin when combined with good diet, environment control and other pharmaceuticals, like Antibiotics, for extreme conditions, like pus oozing.

Costs

Most treatments are very affordable.

Resources

WebMd.com Tips
MayoClinic.org

Conditions

Toe Nail Fungus

When fungi infect a nail, the result can be an infection of nail fungus called onychomycosis. A white or yellow spot appearing under the tip of the nail may be the first sign of a nail fungal infection. The nail may become discolored, thickened and develop brittle crumbling edges as the fungus goes deeper into the nail. The condition is usually not painful and often has no other symptoms, but it is unsightly and can be painful for some people. If the nails become very thick, wearing shoes may be uncomfortable unless you trim down the thickness. However, you must use great care when trimming the thickened nail, because excessive bleeding may occur if you cut into the quick.
What Does Toe Nail Fungus Look Like
When a nail is infected, a condition called onycholysis may also develop, which causes the nail to separate from the nail bed. Onycholysis may cause pain in fingertips or toes and produce a faint odor. Toenail fungus can also cause serious complications for people with diabetes or for people with suppressed immune systems.

Toenail fungus infections are often hard to treat, because it is difficult to reach the infection that embeds itself inside the nail. Nails may clear up for a time after treatment only to have the condition recur later. However, there are various home remedies as well as medications available to treat nail fungus. A complete cure of the condition may take as long as a year and sometimes longer.

Symptoms

  • Nails with distorted shapes
  • Thickened nails
  • Nails with crumbly, ragged or brittle edges
  • Nails with a dull appearance
  • Debris build up under the nails causing them to become discolored or to darken

After a fungal infection gets started in a nail, it will usually remain indefinitely unless it is treated, so begin to treat the condition at the first sign of nail fungus.

Risk Factors

  • Living in a warm climate
  • Working in a damp or humid location
  • Shoes and socks that do not absorb perspiration and that hamper ventilation
  • Walking in damp public shower rooms, gyms and swimming pools without shoes on your feet
  • Heavy perspiration
  • Family history of the condition
  • Older age
  • Being in poor health
  • Having athlete’s foot or psoriasis
  • A weak immune system, poor circulation or diabetes
  • An injured nail, injured skin or an infection

Older people usually have reduced blood circulation, and their nails grow slower and get thicker as they age, causing a greater risk for infection. Men tend to be more prone to toenail fungus than women, especially if they have a family history of the condition.

People with immune systems weakened by AIDS, leukemia, cancer treatments or other medication and those who have diabetes or have had an organ transplant should see a doctor immediately if they have symptoms of nail fungus. These infections can spread to other areas of their bodies and cause serious problems. Diabetics frequently have an impaired nerve supply to their feet because of poor blood circulation and have a greater risk of developing a serious skin infection called cellulitis. Even a seemingly minor injury or nail fungal infection can cause potentially serious consequences for people with diabetes.

Even people who do not have weakened immune systems may experience pain and permanent damage to their nails from fungal infections.

Causes

Molds and yeasts or a group of fungi called dermatophytes can cause nail fungal infections. These fungi are microscopic organisms and can survive without sunlight. The warm, moist environments in showers and swimming pools are ideal places for these microscopic organisms to live, and they can attack your skin even through invisible cuts or a tiny separation between your nail and nail bed.

They typically cause infections only when your exposure to warmth and moisture is continuous. Toenail fungus occurs more frequently than fingernail fungus, because shoes provide a perfect warm, moist environment for fungi to flourish, and the blood does not circulate in the toes as well as it does in the fingers, so your immune system does not fight against the infection as effectively in the toes. People over 60 years old usually have a slightly weakened defense against the invasion of fungi, so they are more prone to develop toenail fungus as they age.

Prevention

It is always better and easier to prevent an infection than to attempt to cure it, so here are a few tips to help prevent toenail fungus:

  • Always use good hygiene, keep nails clean and wash your hands after touching a nail that has infection to prevent spreading it to other nails.
  • Keep nails trimmed short and straight across, and file thick areas of your nails.
  • Dry your toes well after swimming or bathing.
  • Wear synthetic socks to draw moisture away and to help keep your feet dryer than they would be if you wore wool or cotton socks. During cold weather, you can wear wool or cotton socks over the synthetic socks to keep your feet warm. If your feet perspire, change your socks frequently. Remove your shoes periodically, and wear open-toed shoes occasionally.
  • Do not cut or tear the skin around your nails to help prevent germs from invading.
  • Wear shoes or flip-flops in public showers and around pools.
  • Treat your feet and the insides of your shoes with anti-fungal powder or spray.
  • If you get pedicures, either bring your own instruments, or ensure that your nail salon sterilizes their instruments before using them on your toes.
  • Do not trap moisture on your nails by wearing polish or artificial nails.

Tests and Diagnosis

Psoriasis, contact dermatitis, yellow nail syndrome, nail bed tumor and other conditions can appear to be a nail fungal infection, so your doctor will need to scrape some of the debris from under your infected nail and analyze it to identify the cause of your infection. Your doctor can examine the debris under a microscope or culture it in a lab. Yeast and bacteria microorganisms as well as fungi can infect your nails, so your doctor can decide on the best treatment when he or she knows what is causing your infection.

Cures and Remedies

Pharmacutical remedies

Toenail fungus is usually hard to heal, and it often recurs after healing. You can get non-prescription ointments and creams to treat it, but they usually are not very successful in curing the infection.

Prescription Lacquer

If your infection is not severe, your doctor may prescribe ciclopirox, an anti-fungal nail polish called Penlac, for you to apply to your nails and skin every day for about a year. You should apply the polish daily for a week, and then use alcohol to wipe off the layers of Penlac and start the process again, keeping it up for a year. It has been effective in clearing some toenail fungus infections when used as directed, and it is usually more effective when used in combination with topical urea cream. Ciclopiroxolamine and butenafine are also used to treat nail fungus and are effective when used every day for a year or longer.

Topical Medications and Lotions

Your doctor may advise you to use other topical anti-fungal medications, and apply them along with a non-prescription lotion that contains urea, which helps them absorb faster. Your doctor may decrease the amount of infected nail to treat with a process called debridement – filing the surface of your nail. That process may increase the topical medications effectiveness. Topical medications normally do not cure the toenail fungus unless you use them in combination with oral medications.

Oral Medications

Your doctor may recommend an oral anti-fungal medication like terbinafine – Lamisil, or itraconazole, – Sporanox. Studies show that these products are the most effective for treating toenail fungus. When you take these medications for six weeks to three months, you should grow a new nail without infection, taking the place of the infected nail. It may take more than four months to get rid of an infection with these medications, and the infection may return if your feet remain in a warm, moist environment. When you use terbinafine in conjunction with amorolfine nail lacquer, it can be more successful and produce more cost effective results.

Oral medication is frequently recommended for people who experience pain or discomfort due to a nail infection, have diabetes or cellulitis and for those who dislike the appearance of their infected toenails and want an effective treatment for it.

Side Effects

Possible side effects of anti-fungal drugs can be as minor as skin rashes or as severe as liver damage. Consequently, doctors may advise people who have liver disease, congestive heart failure or are taking certain medications not to take anti-fungal drugs.

Surgery

If you have a very painful or acute nail infection, your doctor may recommend surgical removal of your nail. You will probably grow a new nail to take its place, but it may be a year long process for it to completely grow back. After removing the infected nail, your doctor may treat the nail bed with ciclopirox to help prevent recurrence of the infection.

Photodynamic Therapy

Photodynamic therapy involves using a laser to irradiate the nail after treating it with an acid. The laser light source kills fungus in the nail bed. Physicians have been using a Noveon-type laser for some types of cataract surgery, and it is now proving to be quite effective at treating toenail fungus with no pain. Even common laser pointers can aid the appearance and growth of an infected nail when they are pointed close to the nail for a few minutes each week.

Home Remedies

Some people prefer to treat toenail fungus with home remedies because they are less expensive, and the medical treatments are not always effective. These home remedies have no controlled clinical trials to prove their effectiveness, but some people have reported that they helped or cured their nail fungus. As with all toenail fungus treatments, it can take a long time six months to a year for any remedy to work, so do not become discouraged and stop the treatment too quickly. If you are persistent, you may find relief for your condition.
Toe Nail Fungus Natural Remedies

Vinegar

Studies have shown that vinegar hampers the growth of certain bacteria. Experts recommend that you soak your feet in a solution of one part vinegar to two parts warm water for 15 to 20 minutes every day. After soaking, rinse and dry your feet well. If the vinegar soak causes irritation, make the solution weaker, or soak for a shorter time or less frequently.

Vicks VapoRub

People with toenail fungus have reported that applying Vicks VapoRub to the affected area has helped with the condition. Your doctor can advise you about how to use this remedy to gain the most benefit from it.

Hydrogen Peroxide

Some people have reported that applying hydrogen peroxide to infected nails daily helps the condition to some extent. The peroxide helps to control the excessive bleeding that occurs if you trim a nail too closely.

Bleach

You may be able to cure toenail fungus with household bleach diluted in water and applied to the toenail.

Use toenail clippers to trim your nails as short as you can without cutting into the quick. This assures that the bleach will reach more of the fungus. File the toenails down from the top, using care not to go through the nails. There are several different methods for treating toenail fungus with bleach.

  • Mix one part of bleach with ten parts of water and apply to your infected toenails with a cotton swab. Leave the mixture on your toenails, and apply a fresh coat of the solution twice a day.
  • Use a bleach pen to apply bleach to your toenails after bathing, and do not rinse it off.
  • Mix one part of bleach to ten parts of water and soak your feet in the solution for 15 to 20 minutes every day. Thoroughly rinse and dry your feet after soaking.
  • You may soak your feet in the mixture for 30 minutes one time a week if your condition is less severe, or to eliminate the possibility of recurrence after a cure.

Keep soaking your feet for at least three months to be certain that your fungus is completely eliminated. If you do not see improvement in a few months, continue the treatment for at least a year before giving up. If you are not consistent with the treatment and let it lapse, the fungus may get stronger, and you will have to start over.

HERBAL REMEDIES

Some natural ingredients are successful in helping to heal fungus, but they may not work very quickly or be as effective as you would like them to be. However, there have been some very effective products developed recently, and they seem to produce successful results rather quickly. The following products were tested and proved to remove toenail fungus and improve toenail appearance dramatically.

ZetaClear has proved to be effective in treating toenail fungus with all natural ingredients. The product proved to be 100% effective in tests, and most users reported improvement in about two weeks. Their toenails were free of fungus after about three months, but some people kept using the product for a while longer to ensure that the infection would not recur. They reported clear, shiny healthy looking nails after using the product. ZetaClear uses natural oils in its formula and is extremely potent, but it does not cause skin irritation.

Fungisil is another highly effective product and produces the same results as ZetaClear, but it may take about a month longer for some people to eliminate toenail fungus. Fungisils success rate is also 100% and leaves users with healthy nails after treatment.

Another natural treatment for toenail fungus is Nail-Rx by Native Remedies. It has a 90% rate of success and provides excellent results for most users. The fungal infection was completely gone after only three months of use for 80% of those tested.

ALTERNATIVE REMEDIES

The following remedies have no scientific verification, but have been effective in treating toenail fungus for some people.

  • Some people report curing toenail fungus with Australian tea tree oil, but there is no verification of its effectiveness.
  • Some studies show that Thyme oil has the potential to be effective in treating toenail fungus.
  • Some people believe that grapefruit seed extract is a natural antimicrobial, but studies show that the antimicrobial activity in the extract may be due to contamination with synthetic preservatives that were probably not made from grapefruit seeds.

Cost of Treatment

  • The cost of laser treatment can be from $1000 to $2500, and insurance policies usually do not cover the procedure.
  • Oral medication may have a cost of around $1000.
  • Natural remedies can cost from about $100 to $200, and many of them are highly effective.
  • Non-prescription creams and ointments are fairly inexpensive sometimes costing less than $20 – but are usually not very effective.
  • Alternative remedies usually cost less than $50, but there are no studies proving their effectiveness.
  • Home remedies are very economical and usually use products that you already have in your kitchen.

It does not seem to matter whether you use prescription medication, natural products or home remedies to treat toenail fungus it takes at least a minimum of three months to cure, and sometimes the process takes over a year. Depending on the method of treatment you choose, it can also be quite expensive. Whichever remedy you decide to use, be patient and persistent, use good hygiene and common sense and then finally say good-bye to toenail fungus.

Conditions

Hangover

What is a Hangover?

A hangover can be best described as the effect of too much alcohol or drug consumption. Many people can associate with a hangover mainly because it is normally experienced the morning after a long and pleasurable night of drinking. There are two types of hangovers. The first type, which is the most common, is systematic. This means the hangover simply affects the internal body systems. The second type of hangover is a drug related condition that causes adverse reactions, intoxication, and possibly an overdose. Although a hangover can be caused by alcohol, it can also be caused by other types of drugs.

The length of a hangover usually depends on the person. Most hangovers will only last during the morning, while some will last for a full 24 hours. The length of the hangover depends on how many drinks were consumed the night before, the body type of the person experiencing the hangover, and the genetic predisposition of the person experiencing the hangover. Another factor can be the type of drink that was consumed and the food that was consumed.
Natural Hangover Cures
There are not a lot of alternative words to the hangover condition. However, other countries use certain phrases, such as œkac by the Polish, œbabbelas in South Africa, œkater in Germany, and œcrudo in Mexico. While these terms will not be common in America, you may call a hangover the œIrish Flu or even œthe high cost of low living. In fact, many terms that people use when they have the hangover.

While some of these terms can be quite tasteless, like the term œTechnicolor yawn, some terms can be quite interesting, like the term œdawn damage. No matter what you call it, the hangover is something that many people have experienced. Many people will continue to experience it, simply because alcohol consumption has become a part of today’s society.

Symptoms Of a Hangover

The main reason why a hangover is so disliked is that there are many symptoms. A hangover can completely ruin your day, especially if you have important things to take care of. Symptoms of a Hangover include:

  • Headaches
  • Nausea
  • Photophobia, or the dislike of light
  • Irritability
  • Bloodshot eyes
  • Indigestion
  • Thirst
  • Noise sensitivity
  • Fatigue
  • Difficulty concentrating
  • Difficulty making decisions
  • Lack of sleep
  • Dizziness
  • Rapid heartbeat
  • Shakiness

The symptoms of a hangover can vary from person to person. In addition, the seriousness of your hangover depends entirely on the amount of alcohol that you consumed and the steps that you took to prevent the hangover from happening. A hangover can cause many problems. As a result of the headache, you may become extremely irritable. This could ruin your relationship with others, especially if you consume alcohol on a regular basis.

Hangovers can affect your entire life, especially if you have to go to work the next day. This is because a hangover can affect your ability to function in every day life. It also affects your ability to make decisions and concentrate. Since your body is dealing with so many things at once, you may not be able to function properly. Although it may not seem like at the time of your alcohol consumption, your body will be in havoc the next morning.

Not Sleeping Enough

It is dealing with your dehydration, your upset stomach, and other problems. On top of that, if you have not had enough sleep, your body is not able to cope with your hangover. Because of this, many people often choose to drink the night before they have to do anything important. It has to be planned out. When it is planned out the body can be given a day to cope with the hangover. Of course, this can be stopped if you know how to pace yourself and limit that amount of alcohol that you consume. There is a difference between having fun and drinking to excess.

If you or someone you know is experiencing the following symptoms, you may need to call a doctor:

  • Confusion or disorientation
  • Persistent vomiting
  • Seizures
  • Slow breathing or irregular breathing
  • Blue tinted skin or pale skin
  • Hypothermia or cold skin
  • Unconsciousness

This could be a sign of alcohol poisoning. This is a result of too much alcohol in the system. While the hangover is a mild condition, alcohol poisoning can become extremely lethal.

What Alcohol Does To Your Body

Previously in this article, the symptoms of a hangover was mentioned and described. You may be wondering about how the alcohol causes these symptoms. Alcohol does many things to your body, which in turn causes the next morning’s symptoms. If you were to know what alcohol does, you may be able to take preventative measures.

Many people know that alcohol produces more urine, or causes you to urinate more often. This is a result of your body trying to clean out your system. Since you are using the bathroom often, the alcohol is causing your body to suffer from dehydration. Alcohol also causes an inflammatory response from your immune system. Because of this, certain agents can be triggered that can keep you from focusing on certain tasks. This can also affect your overall mood.

Alcohol can irritate the lining of your stomach. It increases the production of stomach acid in your body. This keeps your stomach from fully emptying itself. This may cause abdominal pain, nausea, and of course, vomiting.

Falling Blood Sugar

Your blood sugar can fall because of drinking too much alcohol. This could cause you to feel tired, weak, and upset. Things can annoy you easily and you may be shaking uncontrollably.

Alcohol increases your blood flow. As a result, your blood vessels may expand, causing extreme headaches on your part. Additionally, although alcohol makes you sleepy, it decreases the quality of your sleep. Since you need sleep in order to recharge your body, this could affect you significantly.

Causes of a Hangover

The most common cause of a hangover is alcohol. It can be caused by drinking too much alcohol. For some people, one drink is enough to cause a hangover. Your intoxication level depends on the size of your body. For example, if you do not weigh much, you have a higher chance of being more affected by one drink. Studies have shown that women are likely to have a hangover after three or five alcoholic beverages. Men are likely to have a hangover after five or six beverages. This is because men have more water in their body than women, and their body can soak up the alcohol easier.

Of course, these numbers can change if there are other factors that help or hurt your position.

Risk Factors

Nearly anyone can have a hangover. However, there are certain factors that can change how sever your hangover is. One common risk factor is the type of alcohol that you drink. For example, it is common knowledge that white liquor has less of a chance of causing a hangover than brown liquor. Examples of brown liquor include bourbon, scotch, tequila, brandy, or and red wine. A common example of white liquor is vodka. Even though vodka is less likely to cause a hangover, it can still cause a hangover if too much of it is consumed.

You may be wondering why brown liquor is more likely to cause a hangover. In brown liquor, there is a high level of congeners in brown liquor. This can contribute to hangovers. Congeners are used to change the coloring and the flavor of alcohol.

What you do before you begin drinking also affects your chances of receiving a headache. For example, if you were to drink on an empty stomach, you are more likely to get a hangover the next morning. You are also more likely to become intoxicated more quickly. This is because there is no food in your body to soak up some of the alcohol that you are consuming.
Treating Hangovers
If you use other drugs while you are drinking, your chances of a hangover are increased. The drug that you use could be illegal, but even nicotine can increase your chances of a hangover. In addition, if you do not get enough sleep after you have become intoxicated, you will probably have a hangover. This is because your body needs rest after having gone through so much.

If you have a family history of alcoholism, you may be genetically predisposed to hangovers after consuming alcohol. Your body could absorb alcohol differently than others. Consequently, if you regularly consume alcohol, your body may build up a tolerance. This could keep you from having many hangovers.

Prevention Tips

Many people probably try to find the secret to not getting the hangover. However, there is no real cure to a hangover. There are certain things that you can do that may reduce the pain. The true key is to not over indulge in alcohol consumption. If you follow the following steps, you could possibly prevent a hangover.

  • Do not drink alcohol on an empty stomach. In fact, if you were to eat food with fat in them, you are more likely to soak up the alcohol. Pizza is a good example of this.
  • While you are drinking, pace yourself. It is important that you do not drink too much. Do not drink everything at once, either. A good idea is to drink maybe once alcoholic drink each hour.
  • While you are doing this, you might want to sip on water in between drinks. This can keep your body hydrated and balance the fight between alcohol and water.
  • Consistency is what may keep you from a horrible hangover in the morning. For example, if you are drinking brown liquor, do not switch to white liquor. Try drinking only one type of liquor, and do not change brands. If you stay consistent, you reduce your risk.
  • As mentioned before, if you want to avoid a hangover, you should watch out for your limit. If you know that you have had too much, you may want to stop drinking. If you are intoxicated and you know that you are starting to lose yourself, this is a sign of having too much to drink.

Tests and Diagnosis Considerations

If you may think that you have a hangover, you might want to take into consideration anything else that may affect your body. For example, other medical conditions may cause the same symptoms. This may include meningitis, which causes photophobia.

Medications can cause symptoms that are mistaken for hangovers as well. These medications include chloral hydrate and Dormel. If you are taking medication, make sure that you are not experiencing any serious side effects. Additionally, if you were exposed to chemicals or a type of toxin, this may be the cause of your symptoms.

Treatment Options

When you have a hangover, there is no doubt that you are in extreme pain. There are certain things that can help with this, however.

Since you are dehydrated as a result of the alcohol, you could try drinking water or fruit juice. Whatever you do, avoid drinking alcohol when you wake up in the morning. There is a myth that drinking alcohol the morning after will cure your hangover. This is not true. It will postpone the hangover, but this is all it does. Remember that alcohol caused the problem in the first place, and more alcohol will make it worse.

Since alcohol is prone to lowering your blood sugar, you might want to try eating a snack. Toast and crackers can raise your blood sugar level. Additionally, you might want to eat foods that can replace the salt and potassium in your body. This may include bananas and the crackers that can raise your blood sugar level. Eating eggs can also help remove the alcohol toxin from your body, since it contains cysteine. Cysteine breaks down the acetaldehyde in your body.

Painkillers

Another easy way to treat your hangover is to simply take painkillers. This can ease your headache and other symptoms. However, if you take painkillers after you have finished drinking, this will not do anything. It could cause possible liver damage, but it cannot prevent a hangover. This is because the painkillers will likely wear off by the time you wake up in the morning. Additionally, by digesting painkillers you are giving your liver something else to digest while it is still trying to handle the alcohol. Pain relievers can be a bad idea if you have consumed too much alcohol. Aspirin has the potential to irritate your stomach, while Tylenol can cause liver damage.

Many people just take painkillers and go back to sleep when they wake up. This is truly a smart thing to do. If you were to eat food, drink water, take painkillers, and go back to sleep, you are essentially trying to give your body everything that it is missing. Proper sleep can heal your body more than anything else can. If your stomach is upset, you may want to take antacids as well.

Take it Easy

If you are suffering from a hangover, your best chance is to take it easy for the rest of day. You need to give your body time to recuperate. Make sure you drink plenty of water in order to keep your body hydrated. Do not drink soda or coffee. Despite contrary belief, coffee can actually dehydrate your body further. Although it gives you the extra energy that you may need, caffeine can actually make your hangover worse.

Conditions

Head Congestion

Head Congestion

There are four pairs of paranasal sinuses. Frontal sinuses are located above the eyes in the forehead bones. Your maxillary sinuses are the largest. They are found in the cheekbones and under your eyes. Ethmoid sinuses are between the eyes and the nose. The sphenoid sinuses are in the center of the head, behind the nose and eyes.

Your sinus cavities have a specific job. They are there to warm, moisten, and filter the air that we breathe. Healthy sinuses will allow your mucus to drain and air to circulate. When they become blocked, they can’t do their job properly. Millions of people suffer from blocked sinuses. This often leads to head congestion.

Symptoms

The symptoms of head congestion are very common. You may notice nasal stuffiness. Pain and/or pressure in your head, face, and eyes. You may have a cough and/or runny nose. Your eyes may water and itch. Some people notice that their ears feel clogged.They have a low sense of smell. You may notice increased fatigue. Some people say they feel dizzy at times.
Treating Head Congestion
What causes head congestion? There are a number of possibilities. Check with your doctor for a positive diagnosis. There are some common and well known causes for head congestion. A cold or a flu will often cause congestion. Allergies are on the rise, a vast number of people suffer from nasal symptoms because of an allergic reaction to certain substances.

A deviated septum can cause sinus symptoms. Your doctor can determine if this is the case for you. Certain medications may cause nasal symptoms. If this becomes bothersome, check with your doctor. A sinus infection is a common ailment. People with a sinus infection will notice facial pain and sensitivity. They may notice a yellow or green nasal discharge. A sinus infection is known to cause severe head congestion.

There are other possible causes for head congestion. Some of them can make your syptoms worse:

  • Lack of sleep. If you are prone to sinus symptoms, it is important to get plenty of sleep.
  • Lack of water. Try to drink plenty of fluids throughout your day. Water, juice, and tea are all good choices. Stay away from caffiene. This can make your symptoms worse.
  • Lack of exercise. Believe it or not regular exercise will help with your head congestion.
  • Some people have blocked sinuses. Your doctor may order a CT scan or an MRI. This can help determine if there is a blockage in your sinuses. Your doctor can offer you treatment options.
  • Food allergies may be the culprit. Most people think that their symptoms come from airborne allergens. They may not realize that the problem could be their diet. If you suspect that your symptoms may be related to your diet, try keeping a food diary. Note any reactions to what you eat.
  • Having a cold or flu can cause head congestion. If you have a fever, it is likely to be the flu. If you think you have the flu, see your doctor as soon as possible.
  • New research suggests that there may be a link between head congestion and gastroesophageal reflux. If your reflux is severe enough, it can reach the nasal area. Over the counter Proton Pump Inhibitors have been known to relieve congestion.

Treatment

  • There are a number of remedies available to treat head congestion. The choice is yours.
  • Pseudoral (Sudafed)– This works to shrink blood vessels and swollen membranes in your nasal passages. It helps nasal congestion. Choose a non-drowsy formula. Take 1-2 tablets every 4-6 hours.
  • Nasal Sprays Can be effective but if used too often they can lead to rebound congestion which may make your symptoms worse. Use with care.
  • Tylenol Cold and Head Congestion is an analgesic, decongestant, and cough suppressant. It helps reduce swelling in your nasal passages. It also helps with pain and ends a dry cough.
  • Nasal adheisive strips can be placed on your nose, to make breathing easier. This can be helpful at bedtime.
  • You may want to try a gentle saline nasal spray. These are safe and can be used several times a day.
  • Increase the humidity in your home. Find a good vaporizer or humidifier. Moist air helps to loosen mucus. You may also find it helpful to take a warm bath or shower.
  • Nasal irrigation will help clear your nasal passages. This is a fairly inexpensive option. You can choose from many different brands. Check your local drugstore, many people swear by these products.
  • Zinc lozenges are known to help reduce the duration of cold symptoms. However, there is no proof that it can help head congestion.
  • Vitamin C– A daily dose can help relieve head congestion and help reduce your risk for a cold.
  • Garlic. Many cultures use garlic as a cure all. It is known to have anibacterial and antifungal properties. In order to get the full effect you should make sure that the garlic is chopped or crushed and raw.
  • Honey mixed into your tea may help you get over a cough or cold.
  • Aromatic and herbal tea, chicken soup, or a salty liquid can help with a dizzy feeling and head congestion.
  • Inhale some steam. You can use a pan of water, a tea kettle, or a hot shower. This will help to loosen thick mucus and open your nasal passages. You should plan to do this for ten minutes, 3 or 4 times a day.
  • Get plenty of Omega 3 fatty acids. Adding this to your diet can reduce your risk of developing alllergies. You can find Omega 3 in fish, fish oil capsules, flaxseed oil, and walnuts.

Acupuncture

People who suffer from chronic head congestion may benefit fromAcupuncture. There is a school of thought that states that accupuncture can help with a variety of medical conditions. It has been know to help with the immune system and the entire body.

Acupuncture involves the use of very thin needles. They are inserted into specific parts of the body in order to regulate the immune response to allergens. Many people believe that acupuncture can restore the body’s natural balance.

If you suffer from head congestion you are in search of a remedy. It may take some time to find the method that works best for you. You have a lot of options. From over-the-counter medications to natural home remedies, you can find relief for your symptoms.

Conditions

Anorexia

Anorexia Nervosa Symptoms

Psychological Symptoms

  • Restricting or ceasing food consumption
  • An intense fear of weight gain
  • Weighing under 85% of normal body weight
  • Excessive exercising
  • Viewing your body as overweight, even when it is thin
  • Secretive about eating or only eating when alone
  • Abnormal eating habits or rituals

Physical Symptoms

  • Constipation
  • Low body weight or rapid weight loss
  • Dry skin
  • Unusually small breasts
  • Thinning hair or hair loss
  • Lack of menstrual cycle or menstrual cycle abnormalities
  • Brittle nails
  • Low body temperature
  • Slower than normal heartbeat (usually less than 60 beats per nute)
  • Low blood pressure
  • Increased tolerance for pain
  • Swollen hands or feet
  • Purplish skin hue
  • Yellowish skin hue on hands

Causes

The cause of anorexia is believed to be a combination of emotional, social, and physical triggers, but the exact cause is unknown.

Genetics are believed to be one of the largest factors in developing anorexia. Individuals who develop anorexia are more likely to have a family history of eating disorders, mood disorders, depression, anxiety, and obesity.

Sometimes anorexia can be partially caused by over dieting, which alters the way the body metabolizes food. This causes individuals to become more susceptible to eating disorders.
Natural Anorexic Treament
In some individuals, trauma or personal difficulties can result in the development of anorexia. This is especially common in teens and young adults. External stresses, such as a death, trauma, divorce, or move can trigger the onset of anorexia.
It is also believed that particular personality traits can cause anorexia, such as low self-confidence and perfectionism. This can be due to social or family pressures.

Risk Factors

  • Personality traits, such as low self-esteem, and perfectionism.
  • Emotional conditions, such as depression, and anxiety.
  • A family history of anorexia, bulimia, obesity, depression, or anxiety.
  • Family, social, or cultural pressures that emphasise perfection and physical beauty.

Prevention

There are currently no known methods of preventing the development of anorexia. Most doctors recommend early recognition of the symptoms and immediate treatment. If you or someone you know may be suffering from anorexia, visit the doctor immediately and get help.

Prevention for Parents

Parents should educate themselves about the causes and symptoms of anorexia. Most doctors believe that anorexia is caused, at least in part, by social and family pressures. It’s important that parents speak with their children about developing a healthy body image. Parents should also promote positive thinking through compliments and constructive criticism.

Additionally, parents should teach their children how to lead healthy and active lifestyles. Exercise should be fun and an important part of every childern’s life. Parents should educate their children about ways to take care of their bodies and live healthy lives.

Parents should avoid punishing or rewarding children through the use of offering or restricting food. This can create a negative association with eating that may lead to the development of anorexia.

Diagnosis

There is no standard test for determining whether or not an individual is suffering from anorexia. The symptoms of anorexia are usually fairly apparent and can be diagnosed through observation or patient information.

If patients appear to be suffering from an eating disorder, the doctor will usually ask him or her a series of questions. The questions will help the doctor determine whether or not an eating disorder is the cause of the patients symptoms.

Additionally, the doctor will check patients for signs of malnutrition, which is caused by not obtaining the proper level of nutrients from food.

There are several other tests and exams that are commonly administered to patients exhibiting symptoms of anorexia, including:

  • A standard physical examination. The doctor will check the patients heart, blood pressure, weight, lungs, skin, and hair. This will help determine whether or not the patient is experiencing malnutrition.
  • The doctor will also look through the patients medical history to determine the patients mental, emotional, and physical health. This will help the doctor rule out any other causes of the symptoms.
  • A mental health assessment will most likely be performed by the doctor or another trained professional. This will help determine if depression, anxiety, or any other emotional disorder is causing the symptoms of anorexia.
  • Blood tests may also be administered to check for signs of malnutrition.
  • An x-ray may be performed to determine whether or not the patient has experienced bone weakening as a result of malnutrition.
  • Heart or kidney tests are sometimes performed in severe cases of anorexia or weight loss that may have lead to organ damage.

Treatment Options

Individuals suffering from anorexia need to seek immediate medical intervention. Generally, this involves seeing a general physician and a counselor that can work through the emotional issues associated with anorexia. While there is no set treatment plan for anorexia, the disorder is considered to be a treatable condition.

The counselor will help patients work through the underlying causes of anorexia, which are usually emotional issues or pressures from family, friends, or society. Assessing and working through the underlying causes of anorexia is vital to a proper treatment plan. Only treating the issue at its surface will encourage the anorexia to return throughout the patients life.

Anorexia treatment becomes much easier once the body gains weight and is able to heal. Once the body is able to pull itself out of starvation mode, the mind and body begin to work their way back into sync. This allows the individual to think more clearly and make decisions about their physical and mental health.

Behavioural family therapy may also be recommended, especially in cases involving parents, children, or spouses. The therapy will help train the family to deal with the issue of anorexia. Family members will learn how to be more supportive and understanding of the individual suffering from anorexia. This will help develop a support system for the patient that can help lead to a faster and lasting recovery.

Group therapy may also be recommended. Group therapy provides an atmosphere that is comfortable and encourages discussions. Many individuals suffering from anorexia find encouragement in other people battling the disorder. Group therapy can also build a strong support system for the patient.
Anorexia Remedies
Parents of children or teens suffering from anorexia may be encouraged to take control over the childern’s eating habits.

This will allow the parents and the doctors to ensure that the child is getting the nutrients that he or she needs to recover and return to a healthy weight.

The child will slowly earn back his or her right to determine when and what he or she eats.

Hospitalization

In severe cases of anorexia, hospitalization may be necessary. Patients may be admitted to a hospital if they are believed to be at risk of suicide, starvation, or a medical crisis. The hospital will ensure that the patient is stable and capable of continuing treatment outside of a medical facility.

Individuals who are not considered high risk are usually treated at an outpatient facility.

Home Remedies

When treating anorexia, the largest concern is nutrition and weight gain. The best home remedy for anorexia is a balanced diet. Individuals suffering from anorexia should start their treatment by eating several small meals throughout the day. Eating as much as possible and as often as possible will result in the stomach slowly stretching to accommodate more food. As more food is consumed, the body is better able to heal and the mind achieves a higher level of clarity. This will improve the Individuals ability to recover from anorexia.

While eating a balanced diet is the best remedy for individuals suffering from anorexia, it can also be a treatment that is difficult to maintain. Many individuals with anorexia have difficulty feeling hungry and may have stomachs that are too small to accommodate large meals.

There are a number of home remedies that can help increase appetite, which will lead to weight gain and adequate nutrition in individuals with anorexia.

Fresh Fruits & Natural Remedies

Fresh fruits can effectively treat anorexia because they promotes an increase in appetite. Those suffering from anorexia should eat 2-3 oranges per day to increase appetite. Apples also effectively increase appetite and provide fiber that encourages proper digestion.

One of the most popular home remedies for the treatment of anorexia is ginger and rock salt. The ginger should be cut into a small piece with the skin removed. A paste should be created by smashing the ginger and adding a few drops of lemon juice, a small pinch of rock salt, and a black pepper. This paste should be eaten once daily on an empty stomach and is said to increase appetite.

A salad eaten before each meal is another effective treatment for anorexia. The salad should have a small sprinkle of rock salt, pepper, and lemon. This will create an appetite in individuals with anorexia and encourage them to eat larger meals.

Garlic is another effective anorexia treatment. Those suffering from anorexia should boil 3-4 cloves of garlic in a mug or bowl. Lime juice can be added to improve the taste or the garlic water can be combined with other ingredients to create a soup. This recipe encourages a strong appetite and should be taken two times a day.

Spicy Foods

Many people believe that spicy foods help create a strong appetite. Individuals suffering from anorexia may benefit from eating several spicy meals per week.

Walnuts

Walnuts and almonds are a good source of nutrients and also help improve emotional health. This can help treat the underlying emotional causes of anorexia.

Yoga & Meditation

Yoga, meditation, and a personal journal can all help combat the emotional causes of anorexia. Good mental health is the key to recovering from anorexia.

In addition to home remedies, there are a number of herbs that have been proven to promote appetite. These herbs can be boiled into a tea or used as dressings for salads.

  • Chamomile
  • Marjoram
  • Hawthorn
  • Myrrh
  • Gentian
  • Hops
  • Thyme
  • Wormwood
  • Sage
  • Tarragon
  • Lavender
  • Yarrow
  • Centaury
  • Rosemary
  • Basil

Pharmaceutical Remedies

There currently are no medications that specifically treat anorexia, however, many doctors will prescribe medications to treat the underlying causes of anorexia. These medications will usually be in the form of an antidepressant medication, which will help the individual return to a normal state of emotional health. Antidepressant medications help with a variety of emotional and mood disorders, which may cause or contribute to anorexia.

It is important that individuals suffering from anorexia talk to their doctor before taking any medications. This includes medications that are not a part of the anorexia treatment plan. Anorexia causes the body to shrink in size, which can result in medications building up in the body in an amount that is too high to process and can be dangerous. Additionally, changes in the body due to anorexia can decrease or increase the effectiveness of various medications.

Patients experiencing malnutrition will be either placed on dietary supplements or sent to a dietitian or health care specialist. Ensuring that the patient is not suffering from malnutrition is an important step towards the recovery process. Malnutrition can cause a number of painful and long term side effects and must be treated immediately and thoroughly.

Antioxidants

N-Acetylcysteine

N-Acetylcysteine (sometimes written N-Acetyl Cysteine), abbreviated NAC, is a metabolite of cysteine, a non-essential amino acid that is both found in foods and synthesized by the body from the amino acid methionine. In the body, NAC is rapidly broken down into intracellular glutathione, a powerful antioxidant that detoxifies harmful chemicals into less damaging compounds. NAC supplements are taken to help protect the body against a wide array of environmental pollutants from cigarette smoke and automobile exhaust to inorganic herbicides.

NAC is marketed as a prescription pharmaceutical under a number of trade names including Mucomyst, Mucolysin and Acetadote, available in a variety of different dosages. NAC is also marketed under its own name as a food supplement.

Main Uses of NAC

NAC has two main clinical uses. It’s commonly used in hospital setting as an adjunct to respiratory therapy in the treatment of emphysema, bronchitis, tuberculosis, bronchiectasis, amyloidosis, pneumonia, cystic fibrosis and other conditions that result in the production of thick mucous. It’s also used as the first line of defense against paracetamol (acetaminophen) overdose. NAC has many other clinical applications as well, some well established, some under investigation.

When taken orally, NAC can cause severe gastrointestinal side effects including vomiting, nausea and diarrhea. According to research from the University of Maryland Medical Center, NAC also acutely lowers the levels of homocysteine (tHcy), an amino acid linked to heart disease.
NAC Uses & Benefits
NAC is known to interact with certain prescribed blood pressure and immunosuppressive medications as well as cisplatin, doxorubicin, nitroglycerin and isosorbide, and oxiconazole; if you are taking any of these medications, check with your physician before you start taking NAC as a food supplement.

Sources of N-Acetylcysteine (NAC)

Cysteine, the non-essential amino acid from which your body synthesizes N-Acetylcysteine, is found in foods like poultry, pork, yogurt, ricotta and cottage cheese, egg yolks, red peppers, garlic, onions, broccoli, Brussel sprouts, oats, and wheat germ.

Cysteine/NAC supplement tablets or capsules are available over the counter and can be found in many pharmacies, health food stores and specialty supplement stores as well as online.

As a prescription medication, NAC is marketed under the following trade names:

  • For mucolytic inhalation therapy: Asist, Mucomyst, Mucosil
  • As an intravenous injection in the treatment of paracetamol/acetaminophen overdose: Asist,Parvolex, Acetadote

N-Acetylcysteine Use

N-Acetylcysteine has proven to be an effective therapy in a variety of clinical situations. Additionally, the metabolite is widely used as a nutritional supplement for its properties as a selective immune system enhancer and as protection against environmental toxins.

Therapeutic Uses

Mucolytic Therapy: A.L. Sheffner first demonstrated the mucolytic properties of N-Acetylcysteine in 1963, and NAC quickly became a part of standard clinical practice for the treatment of chronic lung diseases. NAC dissolves mucus by liquefying its disulfide bonds. NAC also stimulates glutathione synthesis within the body: glutathione reduces pulmonary inflammation by neutralized harmful oxidants introduced into the lungs; this helps maintain the normal composition of mucus, keeping it from becoming too viscous.

NAC has also been administered with good results to patients suffering from interstitial diseases affecting the tissue and space around the air sacs of the lungs. There is also some evidence that it may reduce exacerbations in chronic obstructive pulmonary disease.

Initially NAC was only administered by inhalation, but more recently it’s been given orally as well. Peak blood levels are reached one hour after oral administration.

Paracetamol/Acetaminophen Overdose: Intravenous N-Acetylcysteine is indicated for the treatment of paracetamol/acetaminophen overdose.

Acetaminophen is the most widely used pain reliever in the world, easily available over the counter. Most of us have used at one time or another for headaches or minor aches and pains. It’s generally safe at recommended dosages – not more than 4000 mg a day.

Dosages of more than 7000 mg in a single day, however, can be fatal although often the first symptoms do not occur until 12 hours after the acetaminophen was swallowed. Evidence of liver damage may occur within two to five days after the toxic dose, and death from liver failure follows. Even in the absence of liver damage, renal damage can occur up to 14 days afterwards.

The symptoms are due to the accumulation of an oxidizing agent called N-acetyl-p-benzoquinone imine that is normally detoxified by glutathione. In the presence of large amounts of this metabolite, glutathione levels in the body diminish. Cell death occurs when glutathione levels drop to less than 25% of normal.

NAC gives the body a way of boosting its own glutathione production and thus acetaminophen-induced cell damage and death. Optimally, NAC should be administered intravenously within 12 hours of the toxic ingestion; if it’s given more than 16 hours after ingestion, it will protect the body against further cell damage but it cannot reverse the cell damage that has already occurred.

Kidney Damage Following Contrast Dye Injection: Physicians may order a prophylactic dose of N-Acetylcysteine for patients undergoing diagnostic imaging scans who are at risk for developing kidney damage secondary to the injection of necessary high-contrast dyes.

Significant but inconsistent evidence has been put forward touting N-Acetylcysteine’s benefits in a variety of therapeutic situations.

  • Chronic bronchitis associated with smoking and emphysema. While one double-blind, placebo-controlled study involving 1,400 human subjects found that NAC taken daily at a dosage between 400 mg to 1,200 mg reduced the number of acute bronchitis flair-ups, another study on a smaller sample showed no effects at all.
  • Influenza. In a double-blind, placebo-controlled study of 262 seniors, 600 mg of oral NAC administered twice daily was shown to help prevent the development of serious influenza symptoms. Only 25% of the NAC group developed serious symptoms while 79% of the placebo group did.
  • Angina Pectoris. A double-blind, placebo-controlled study of 200 individuals suffering from heart disease found that the combination of nitroglycerin and NAC was more effective in reducing the incidence of heart Attacks than either NAC or nitroglycerine alone.
  • Female Infertility. A double-blind, placebo-controlled study of 150 women suffering from infertility showed that NAC enhanced the effectiveness of clomiphene. Twenty percent of the group using both NAC and clomiphene got pregnant as compared to 0% of the group using a placebo plus clomiphene.
  • Cancer risk. Some evidence seems to indicate that NAC can offset the carcinogenic effects of smoking and reduce the risk of colon cancer.
  • Supportive therapy for HIV.
  • Mental health disorders including schitzophrenia, obsessive-compulsive disease, cocaine dependence and gambling addiction

As a Dietary Supplement

N-acetylcysteine is a naturally occurring amino acid metabolite, derived from cysteine. While NAC itself does not occur in foods, its precursor cysteine is found in most high-protein foods as well as vegetables such as broccoli and Brussel sprouts. Many people augment their body’s NAC levels by taking it as a dietary supplement. NAC is a precursor of glutathione, a potent antioxidant found in all body tissues that plays a vital role in the detoxification of harmful substances.

Antioxidants protect the body against toxic byproducts of normal cellular metabolism called free radicals. Free radicals interfere with the ability of cells to heal themselves, and free radical mediated reactions are thought by some scientists to contribute to the development of a wide range of maladies including neurodegenerative diseases like multiple sclerosis.

NAC has been proven to enhance T-cell production and some research indicates that it suppresses the replication of HIV in vitro. NAC is also a heavy metal chelator, binding to toxins like mercury and lead and helping to remove them from the body.
NAC Risks
As a dietary supplement, NAC is available in capsules, tablets, powder, and solution. There is no daily requirement for NAC, and optimal levels have not been determined. Typical dosage can range from 250 mg to 2,000 mg per day but the most common dosage is 500 mg, taken twice daily.

There is some evidence that NAC increases the excretion rate of necessary trace minerals; people taking NAC would therefore be well advised to take a multivitamin/mineral supplement as well. While no adverse effects specifically related to NAC’s use by children have been reported, it is never a good idea to give children under 18 dietary supplements without checking with the child’s pediatrician first.

Side Effects of N-Acetylcysteine

Adverse reactions involving the gastrointestinal tract have been reported with N-Acetylcysteine. These include nausea, vomiting, headache, dry mouth, dizziness, and/or abdominal pain. In a few reported cases, NAC use has been linked to hypotension, anaphylaxis, asthma attacks and headache.

NAC potentiates the effects of nitroglycerine prescribed for angina pectoralis and can increase the hypotension, headache and temporal artery dilation associated with that medication.

University of Virginia researchers reported that large does of NAC – equivalent to those found in some body building supplements – increased pulmonary artery hypertension in mice, leading to permanent heart and lung damage.

Shopping N-Acetylcysteine Dietary Supplements

N-Acetylcysteine dietary supplements are widely available in pharmacies, health food stores and specialty dietary supplement stores as well as online. Prices are slightly less expensive online (but that’s before you factor in the freight charges.) NAC will run slightly under $7 for a 100 600 mg capsules if you buy from an online vendor, and around $8 for the same amount if you buy from a store. Of course, prices will vary with location.

Antioxidants

Carotenoids

Overview of Carotenoids

Carotenoids are an important group of vitamers of vitamin A. When referring to a vitamin such as vitamin A, it is important to note that vitamin A is not one substance or one molecule. In reality, vitamin A is a group term to collectively classify organic, chemical compounds that have the same biologic effect on an organism.

These compounds are called vitamers. Retinol, retinal, alpha-carotene, beta-carotene, gamma-carotene, and beta-cryptoxanthin are the most important vitamers of vitamin A. They each have different chemical structures and composition, but have similar effects on the human body, playing important roles in proper nutrition and functioning.

Carotenoids and vitamin A in general play pivotal roles in the normal functioning of the human body. Their roles include helping the body to regulate cell growth, regulate hormones, and help enzymes to act as catalysts in metabolism. Furthermore, carotenoids are strong antioxidants, which can bind to free radicals in the body. These molecules called free radicals can damage cells and cause chronic diseases and cancer.

Fat Soluble Vitamins

Carotenoids and all other vitamers of vitamin A are fat soluble vitamins. Vitamins fall into either of two categories — fat soluble or water soluble. When speaking of the solubility of a vitamin, the term refers to whether or not a molecule dissolves in water or fat. In humans, the water soluble vitamins are the B series of vitamins and vitamin C. The fat soluble vitamins include vitamins A, D, E, and K. For example, a water soluble vitamin like vitamin C is ingested and then metabolized by the body.
Using Carotenoids for Health=
Once the body has used all the vitamin C that it needs, the vitamin C is excreted as urine. On the other hand, a carotenoid like beta-carotene, being a form of vitamin A, is fat soluble. In this case, once the body metabolizes all of the vitamin A that it needs, the excess is stored in the body’s fatty tissue and liver. Fat soluble vitamins can linger in the body for a long time. Given enough time and enough exposure, toxicity can develop.

Carotenoids and vitamin A are necessary for proper growth and nutrition in humans. They are responsible for regulating many of the body’s functions such as metabolism and hormone levels. Deficiencies of a particular vitamin can negatively impact a person’s overall health and well being, causing several problems that range from mild to severe. In extreme cases, severe vitamin deficiencies can lead to birth defects and death.

Vitamin A

Carotenoids are a major group of vitamin A and are mostly plant and fungi derived. The only known animal source of carotenoids is a small insect that likely got a gene that causes it to produce carotenoids from a fungus via cross species gene transfer. They are naturally occurring, organic pigments found in the chloroplasts of plants and are largely responsible for giving red, orange, and yellow fruits and vegetables their vibrant colors. They are also found in abundant amounts in leafy, green vegetables.

Carotenoids can be divided into two major subgroups based on their molecular configuration. One group is the carotenes and the other group is the xanthophylls. These two groups are very similar in chemical structure except that the xanthophylls have oxygen molecules in them.

Discovery and History

Before proper technology and techniques were invented in the 20th century, all sources of carotenoids and vitamin A had to be obtained through food like meats, fruits, and vegetables. In 1947, the Dutch scientists David Adrian van Dorp and Jozef Ferdinand Arens successfully synthesized vitamin A for the first time, allowing for widespread supplementation to undernourished populations to begin.

Vitamin A was discovered in a period from 1906-1907 by Elmer McCollum. McCollum was doing research on cattle, trying to determine why cows fed with wheat only produced offspring with serious birth defects and low birth rates as compared to cows that were fed a diverse diet based primarily on corn. In experiments done on mice, which were cheaper and more practical to experiment on than cows,

McCollum discovered that rats showed similar results in their birth defects and low birth rates when fed diets consisting only of protein. Furthermore, his studies showed that in order to fix the problem, all he had to do was introduce small amounts of animal fats into their diets. McCollum theorized that the animal fats contained a substance that was responsible for the differences. This compound was named vitamin A, which was the first vitamin and the first fat soluble vitamin to be discovered.

Important Carotenoids

Some of the most important and most wide known carotenoids are beta-carotene, lycopene, and lutein.

Beta-carotene is perhaps the most well known carotenoid. As the name suggests, beta-carotene is a true carotene, having no oxygen atoms in its molecular structure. Beta-carotene is a naturally occurring pigment with a red to orange hue that is seen primarily in fruit and vegetables. Beta-carotene is a pro-vitamin of vitamin A. Pro-vitamins are precursors to a vitamin from which a certain vitamin can be manufactured by the body.

Lycopene is a bright red, naturally occurring pigment that is also a true carotene like beta-carotene. Lycopene is thought to be a powerful antioxidant that reduces the chances that a person will develop cancer. It has also been suggested that lycopene may help prevent macular degeneration, prostate problems, and asthma. Lycopene is found in red colored fruits and vegetables including tomatoes, although supplements exist in soft gel form.

Lutein is a yellow pigment and a member of the xanthophyll class of carotenoids found in leafy, green vegetables like kale and spinach. Lutein plays an important role in human eyes. The retina, an area of tissue in the back of the eye responsible for transmitting nerve signals to the brain, has areas on it that have high concentrations of lutein. Lutein helps to pigment this area of the eye, making it darker and less susceptible to macular degeneration. Lutein may also help to prevent cataracts.

Uses of Carotenoids

Vitamin A Deficiency Prevention

Carotenoids are important parts of the diet that can help to prevent vitamin A deficiency. Vitamin A deficiency is a major nutritional problem for millions of people in the developing world who do not have adequate sources of food that can provide the proper levels of vitamin A needed for good health and survival. Vitamin A deficiencies are either primary or secondary in origin. Inadequate supplies of nutrients cause primary deficiencies, while secondary deficiencies come from other underlying medical conditions. Left unchecked, vitamin A deficiency can result in night blindness and a decrease in tear production.

Vitamin A plays an important role in human vision. In the eye, rod cells in the retina that are responsible for detecting light, bind a form of vitamin A called retinal with protein called opsin. Through a series of reactions, the retinal changes forms, which sends nerve impulses to the brain’s visual processing center, allowing people to see. People suffering from vitamin A deficiency have trouble seeing in dim light. Perhaps a more important impact of being vitamin A deficient is the inability to create tears.

Tears are the eyes main defenses against debris and bacteria which can scar the cornea, resulting in blindness. Vitamin A deficiency can also cause a condition called hyperkeratosis where people develop small bumps on the skin that are caused by keratin protein blocking hair follicles. Aside from causing dry skin and itching, hyperkeratosis can make hair fall out over the whole body.

Immune System Support

Carotenoids are a precursor to vitamin A. The body can convert carotenoids in vitamin A, which is important in maintaining a healthy immune system. The immune system is the body’s defense against foreign invaders like bacteria and viruses. Vitamin A plays its role in the immune response by helping the thymus gland to produce specialized cells called T-lymphocytes quickly and efficiently.

When a pathogen enters the body, the immune system detects its presence and sends out these T-lymphocytes to kill the invader. Vitamin A derived from carotenoids can also help in the growth and health of epithelial cells. These cells line the mucus membranes of the body in places like the lungs, nose, and mouth. Mucus membranes secrete fluids that can trap harmful bacteria and viruses before they get a chance to take root and cause an infection.

Antioxidant Properties

Free radicals are molecules in the body that can cause damage to cells. Cell damage can lead to chronic diseases as well as cancer. Carotenoids like lycopene and beta-carotene are known to be powerful antioxidants. Antioxidants are compounds that can bind with free radicals, decreasing their ability to cause cellular damage. Antioxidants have the further benefit of helping to repair previous damage cause by free radicals.

Cell Communication and Cancer Prevention

Carotenoids have been shown to aid in cell communication, which may help in the prevention of cancer. Researchers have found that carotenoids increase the activity of molecules in cells that are responsible for connecting cells to one another through which nutrients and signals may be shared.
Carotenoids & Vitamins
Cancer cells do not have this ability, allowing them to grow out of control. By introducing carotenoids to these cells, scientists have been able to increase the amount of cellular communication between cancer cells and normal cells, leading to the cancer cells behaving more normally.

Sources of Carotenoids and Recommended Amounts

Carotenoids are found in many fruits and vegetables that are bright yellow, orange, or red in color. They are also found in dark, leafy greens. These include:

  • Carrots
  • Pumpkin
  • Winter squashes
  • Sweet potatoes
  • Cantaloupe
  • Apricots
  • Peaches
  • Papaya
  • Mango
  • Kale
  • Tomatoes
  • Spinach
  • Broccoli
  • Peas
  • Turnip greens
  • Collard greens
  • Swiss chard
  • Red peppers
  • Guava
  • Grapefruit

Cooking and processing some carotenoids can cause nutrients to be leached. However, in the case of tomatoes, the availability of the carotenoid lycopene can be increased by cooking. Therefore, lycopene can be obtained more easily from canned and cooked tomatoes better than from fresh ones.

The daily recommended amount of Vitamin A is 900 micrograms per day, with a maximum of 3000 micrograms per day for adult males. In adult females, the recommended amount per day is 700 micrograms, with the maximum amount being 3000 micrograms. Women who are nursing require more vitamin A in order to nurture both themselves and the baby. For women who are breastfeeding, the daily required amount is 1300 micrograms with a maximum of 3000 micrograms.

Carotenoids can be bought as supplements in pill form. Typically, it is possible to find several individual varieties or combinations of carotenoids available online and in health food stores. Prices will vary widely depending on the brand and number of pills in the bottle. On average, beta-carotene pills will cost roughly 7 cents per pill. Lycopene is a bit more expensive and runs between 11 and 13 cents per capsule. Recommended dosages vary with the supplement. As always it is important to consult with a doctor and to read the labels on the supplement before taking it.

Toxicity

Carotenoids are fat soluble, meaning that any extra molecules that are not metabolized will be stored in the body’s fatty tissue and liver. These molecules can stay in the body for a long time because they are difficult to remove once stored in the body’s fat. Over time, given enough exposure, toxicity can develop. The most noticeable sign of carotenoid toxicity is the skin changing colors to an orange hue. This condition is called carotenodemia. Acute poisoning can occur if daily amounts of vitamin A exceed 3000 micrograms.

Symptoms of acute toxicity include nausea, vomiting, headache, dizziness, vision problems, and loss of muscular control. Chronic toxicity happens over a long period of time when daily consumption exceeds 1200 micrograms daily over a period of months. Symptoms of chronic vitamin A toxicity include all of the symptoms of acute poisoning in addition to anemia, fatigue, and bone problems. Vitamin A toxicity is rarely fatal and is treated by maintaining proper hydration and limiting vitamin A consumption.

One interesting side effect of beta-carotene is that it may cause cancer in smokers. Although beta-carotene is a powerful antioxidant, a study has shown that people who took 20-30 milligram supplements were at a higher risk of developing lung cancer than those who did not. Critics of this study argue that smokers were included in the research, which may have skewed the results.

Conclusion

The benefits of ingesting enough carotenoids and vitamin A have been known for over 100 years. Today, vitamin A deficiency is rare in wealthy countries, but continues to be a problem in developing nations. With the advent of commercial synthesis processes, treatment is widely available. In addition, vitamin A has been shown in study after study to promote health and well being, so it is important to maintain proper levels for optimal health.

Antioxidants

Tocotrienols

Tocotrienols, which are members found in the Vitamin E family, are natural agents that, according to scientific research, have tremendous health benefits and may even affect how such illnesses as cardiovascular disease, diabetes, and certain kinds of cancer are treated in the future.

What Are Tocotrienols and Where Do They Come From?

Tocotrienols can be found in certain kinds of oil, rice, wheat, barley, rye, and oats. They are mainly found in the highest concentration in palm oil, which is derived from the palm nut that is commonly found in Africa and often used as a cooking oil. While their benefits are still being researched (tocotrienols account for less than 1% of research done on vitamin E), they are no doubt a point of interest for researchers throughout the world. While they are natural agents, they are generally found in low concentrations that do not have any appreciable benefits when consumed directly from the food source.

Molecular Makeup

Vitamin E, from which tocotrienols are derived, is essentially divided into eight isomers: four tocopherols (alpha, beta, gamma, delta) and four tocotrienols (alpha, beta, gamma, delta). Both groups share common traits, such as the head, otherwise known as the Chroman Ring; the tail, phytyl tail (found mostly in tocopherols); and the hydoxy group, which is the active group head found at the head of the molecule.
Tocotrienols Side Effects

History of Tocotrienols

Tocotrienols were discovered in 1964 by Drs. Pennock and Whittle, from the USDA and Liverpool respectively, who were able to isolate the molecules from rubber. But it wasn’t until the 1980s when their potential benefits were discovered by Drs. Qureshi and Elson from the University of Wisconsin in Madison, who discovered that tocotrienols could lower cholesterol.

During the 1990s, scientists learned about their anti-cancer properties in their research. One man responsible for developing interest in this field of research was Dr. Barrie Tan, PhD. During the 1980s.

Tan was able to extract tocotrienols from rice, palm and later annatto, a red plant primarily found in South America, which led to patents for Caratech and Rangsit Biotech, two companies he founded in the 1980s and 1990s. It is through these extractions that tocotrienols derive their greatest benefits in scientific research and dietary supplements.

Scientific Research and Discoveries

Scientists have researched tocotrienols for their effect on such diseases as cancer, cholesterol, heart disease, and diabetes. Most of the research have concentrated on animal studies, which have yielded promising results. But studies on the effects of the agent on humans are limited and at times inconsistent.

Types of Potential Treatments

Pancreatic, Breast, Prostate, and Skin Cancers

Research scientists have discovered that tocotrienols can decrease the formations of tumors and prevent damage to the DNA and cells. In a 1993 controlled study, rats which were induced with dangerous liver cancer agents had suffered less liver damage when they were treated with palm based tocotrienols. In a 2009 study conducted by researchers at the Department of Nutrition and Food Sciences, Texas Women’s University it was also discovered that a more potent vitamin E isomer called d-delta tocotrienols can be potentially used for chemotherapy treatment for pancreatic cancer.

Significant findings in tocotrienols have revealed potential benefits in the treatment of other forms of cancer. In a 2009 study conducted by the College of Pharmacy, University of Lousiana, Monroe, researchers have learned that palm based tocotrienols, when combined with statins, can have enormous benefits in the treatment of breast cancer.

Research

Not only that, in research conducted by East Tennessee University and MD Anderson Cancer Center in Texas, gamma-tocotrienols can slow down the cultured cell growth of human breast cancer and are three times more powerful than Tamoxifen, a drug used to treat breast cancer. Delta-tocotrienols have shown to cause cell-death (apoptosis) in estrogen responsive and estrogen non-responsive breast cancer cells.

They can also reduce the growth of certain types of cancer, while alpha- and gamma-tocotrienols have prolonged the life spans of mice infected with cancer. Studies have also suggested that tocotrienols can potentially detoxify malignant properties found in prostate cancer cells. A combination of gamma-tocotrienols and chemotherapy drugs may also decrease skin cancer cells.

Cholesterol

In the findings of a 1993 controlled, double-blind placebo study, research scientists have uncovered some interesting information regarding the benefits tocotrienols have on cholesterol levels. For instance, scientists have learned that palm based tocotrienols have the potential to alleviate arteries clogged by cholesterol. Certain types of tocotrienols have been found to be more effective than others, while Y-tocotrienols are more apt to decrease the development of cholesterol within liver cells.

Cardiovascular Diseases and Stroke

Studies have also shown that tocotrienols can have the potential to reduce the risks of cardiovascular diseases, such as carotid atherosclerosis, and stroke. In one human medical research study, patients with carotid atherosclerosis who were given 240 mg of palm based tocotrienols a day for 18-36 months had seen a significant decrease in the amount of cholesterol plaque in their carotid artery.

Palm based tocotrienols can also provide protection against ischemia and reperfusion heart injuries by relieving oxidative stress on the heart. Delta-tocotrienols can slow down the aggression of platelets, while palm based tocotrienols can possibly be an antithrombotic agent. Stroke victims can also benefit from the effects of tocotrienols as a drug treatment.

According to a study funded by the NIH and conducted by the Ohio State University Medical Center (along with Prof. Chandan Sen who published 5-peer viewed papers on the subject), alpha-tocotrienols can protect the brain from stroke-related injuries. Another study conducted by the AJP Heart and Circulatory Physiology have found that gamma-tocotrienols can prevent major damages to the heart after a stroke, as well.

Diabetes

Tocotrienols are a potential form of drug treatment for Type 2 diabetes. Researchers in both India and Malaysia, during a 2009 study, have discovered the benefits tocotrienols have in improving blood glucose, dyslipidemia, and oxidative stress on diabetic lab rats.

Anti-Aging Cosmetics and Personal Care

The more popular use of tocotrienols occurs in the field of anti-aging and cosmetics applications for their antioxidant properties. Tocotrienols can be a potent protective agent against free radicals caused by ultraviolet (UV) and ozone rays.

They can also prevent skin aging and damage caused by oxidative rays. Often an active ingredient in sunscreens, tocotrienols penetrate through the skin at a faster rate than tocopherols and can decrease the UV rays’ penetration into the skin.

Other Potential Health Benefits

Not only do tocotrienols have the potential to aid in the treatment of certain kinds of cancers, cholesterol, and diabetes, but they are also effective in lowering blood pressure. In studies, researchers have found that gamma-tocotrienols can prevent the development of increased blood pressure in Spontaneous Hypertensive Rats (SHR) after three months of application.

Alpha tocotrienols are considered a powerful natural super-antioxident as well, which can provide numerous health benefits in the prevention of free radicals.

Who Uses Tocotrienols and How?

While the research on tocotrienols is still ongoing, it is still recommended to people continue to take Vitamin E and tocotrienols. Anyone can take them. It is recommended that young adults begin taking the supplements and continue usage throughout their life. Tocotrienols are already used heavily in Asia, where it has become a daily part of the diet. Other countries are quickly noticing the benefits of including tocotrienols as a part of the diet as well.

Athletes, joggers, and bodybuilders also take tocotrienols after strenuous activities, such as exercising, for protein and lipid peroxidation, or the damage caused by oxidation on fats.

Regulations and Regional Legal Status

While researchers continue to study the health benefits of tocotrienols, governments have approved their use in dietary supplements as well as food additives. In fact, other countries have been leaders in the use and research of tocotrienols and their overall health benefits. For instance, Japan has approved tocotrienols as an additive in food, while the French government has approved palm based tocotrienols in dietary supplements.

The Health Ministry of Malaysia has also approved them as a dietary supplement. In the United States, the FDA has yet to assign tocotrienols to vitamin E activity. The FDA, though, has identified palm based tocotrienols complex as Self-Affirmed GRAs (Generally Regarded Safe) to be used as an ingredient in foods.
Using Tocotrienols

Health Supplements, Dosages, and Side Effects

Tocotrienols are still available as health supplements and are commonly taken as soft gel capsules, hard shell capsules, liquid emulsifiers, and vitamin premixes. The supplements can also come in lozenges.

Standard dosages can fall between 140 to 360 mg/day, but the more common dosages fall within the 40 to 50 mg/day range. Generally, there are no differences in dosage among children and adults, though children under the age of 10 are advised not to use tocotrienols at all unless under the recommendation of a physician.

Since tocotrienols are derived from vitamin E, there are no known side effects, even when dosages are as high as 2500 mg/day per kilogram in the body.

The Food and Nutrition Board of the Institute of Medicine in the United States and the National Academy of Sciences have no definition for the health benefits or risks, including Estimated Average Requirement, Recommended Dietary Allowance, Adequate Intake, or Tolerable Upper Intake Level, associated with tocotrienols.

Myths

One myth regarding tocotrienols is the idea that their benefits are noticeable even when consumed in natural foods. Some literature even tout the health benefits of consuming a teaspoon of palm oil a day. This is not the case. The amount of tocotrienols found in natural foods like palm oil, barley, wheat, or grain, is so low that there are no appreciable benefits in consuming these foods solely for their supplemental value.

While palm oil has the highest concentration of tocotrienols, one will have to consume two cups of palm oil a day in order to have any benefits. It is only through extracting tocotrienols from these foods, particularly from palm oil, that they can have their full potential as a health supplement.

Consumer Information

Types of Supplements

In order to get the most out of tocotrienols they must be taken as a dietary supplement. The best possible supplements will be organically derived from palm oil. Processed-derived supplements can be useful too, but only if they contain phyto-nutrients which are also found in palm oil.

These nutrients will include phytoserols, squalene, and mixed cartotenoids. Rice-derived tocotrienols and formulas which use phyto-nutrients, such as soy isoflavones, Ginkgo Bilboa, and beta sitosterol, and natural palm tocotrienols combined with phyto-carotenoid are also very good choices.

Costs

Dietary supplements containing tocotrienols are expensive. This is due to the fact that, since the agent exists in very low levels in nature, the extraction process is often difficult and expensive. Generally, the dietary supplement can cost between $30 to $40. The most expensive brands include Nature’s Plus, Twinlab Maxilife, Source Natural, and Jarrow Formulas.

There are less expensive brands, though, such as NSI Tocomin Supra Bio, which sells palm based tocotrienols for $13.77 and Source Naturals for $11.48. While many health food stores such as GNC, The Vitamin Shoppe, and others carry a variety of brands and prices, the best deals can often be found online. Amazon.com, for instance, sells many brands of tocotrienols from $25.14 and lower.

Other online stores such as Vitacost, iHerb, and Nutritiondome also sell brands as low as $25 and less. Before buying, its best to research and bargain shop for the best brands and prices.

Sources

National Institute of Health
Everyday Health
WebMd.Com

Antioxidants

Oleuropein

Description of Oleuropein

Oleuropein is the active ingredient or glucoside, found in green olives and olive leaf. Olive leaf is found on the olive tree. Another active ingredient found in olive leaf is hydroxytyrosol, polyphenols, flavonoids, and Oleocanthal. Oleuropein and olive oil, extracted from green olives and olive leaves, are known in alternative medicine for its medicinal benefits.

Scientists began to evaluate the benefits of oleuropein, olive leaf, and olive oil. These studies began when scientists noticed that individuals in the Mediterranean consistently showed a lower occurrence of heart disease and cancers. The cancers with the lowest incidence were prostate and colon cancers. Scientists attributed this finding to the diet consisting of mostly fruits, vegetables, peas and fish. But more importantly, it is attributed to olive oil comprising the majority of the fat content within the diet.
Oleuropein Uses
Oleuropein or olive oil is known for its anti-aging effects, its antifungal properties, its anti-infllamatory properties, its antibiotic properties and its immunostimulators. Olive leaf extracts have also been known to lower blood pressure. Scientists discovered, in an international study, that olive leaf extract contained twice the antioxidants of green tea extract and 400 percent higher than Vitamin C.

Individuals, who practice alternative medicine, use olive leaf or Oleuropein for the following purposes:

  • Natural pathogens killer: It kills pathogens by preventing pathogens from replicating.
  • Colds
  • Flus
  • Yeast Infections
  • Heart Disease
  • Lowering Bad Cholesterol or Low Density Lipoproteins (LDL)
  • Lowers Blood Pressure
  • Increases Blood Flow
  • Treats Epstein-Barr Disease
  • Treats Shingles
  • Treats Herpes

Because of its remarkable antioxidant properties, oleuropein protects the body from free radicals. When free radicals undergo the oxidation process, they may cause cellular damage if they exist in the body in excess for extended periods of time. Free radicals are highly reactive. Therefore, antioxidants must be introduced to prevent development of diseases such as cancer and other diseases.

Oleuropein is a polyphenol extracted from the leaves, bark, root, and fruit of the olive tree. The olive tree contains agents that make it highly resistant to insect damage and other diseases. Oleuropein is also classified as an iridoid.

This plant substance is present in olive oil and in the olive tree. Another agent contained in oleuropein is elenolic acid. This particular acid is particularly useful in maintaining the body’s immune system. This portion of oleuropein, elenoic acid, balances bacteria, while promoting a healthy immune system.

History and Origin of Usage

The olive leaf extract has been used for thousands of years. The Egyptians and the Mediterranean cultures have long used this particular extract to alleviate a number of health conditions.

Myths Associated with Oleuropein

Thousands of years ago, the Egyptians recognized the olive leaf as a symbol of heavenly power. The Egyptians used the extracted oil to mummify their Egyptian kings. Olive leaf was also used in the 1880s to alleviate symptoms associated with malaria. Biblical references were also made to the olive tree as “The Tree of Life.” Scientists believed the ancient people referred to the olive tree as “The Tree of Life” because of its medicinal properties. Even ancient people recognized the efficacy of the supplement.

How Oleuropein is used

Oleuropein is often found in a tea form. The tea is based upon the olive leaf. While green tea has many antioxidant benefits, oleuropein and olive leaf have double the anti-oxidant effects of green tea. Some of the benefits of oleuropein are listed below:

  • Helps Lower Cholesterol
  • Combats Viruses
  • Prevents Cold Sores and Herpes
  • Possesses Anti-Fungal Properties
  • Possesses Anti-Bacterial Properties
  • Maintains A Strong and Balanced Immune System
  • Fights Common Cold and Flu

Olive leaf extracts or oleuropein may also be found in topical creams. Oleuropein is often found in soaps and moisturizers. The active agent, oleuropein, helps to repair the skin.

Some experts believe that 50 grams of olive oil per day is thought to have an equivalent effect to 0.1 of the adult ibuprofen dosage and use.

Many physicians suggest that the polyphenols in red wine have an antioxidant effect. Similarly, the polyphenols in oleuropein have an antioxidant effect in reducing the oxidation of bad or LDL cholesterol. Olive oil contains more antioxidants than a glass of red wine. However, most enjoy wine over olive oil.

In the form of olive oil, oleuropein may be used in a variety of home remedies as well. Some of the most popular ones are listed below:

  • Promote healthy skin
  • Olive oil contains at least 4 different antioxidants. These antioxidants assist in eliminating free radicals in the body. Free radicals assist in skin aging. Olive oil helps to fight skin cancer and aging.

    Ozonated olive oil is also supposed to soothe the skin as well. Some experts recommend boiling ozonated olive oil until it forms into a paste. Rub the paste onto the skin for soothing and healing promotion.

    Olive oil contains a significant amount of a natural emollient called squalene. Squalene is able to moisturize the skin without leaving a film behind. Olive oil is also rich in vitamins A and E. Both of these vitamins contain healing properties for the skin. Polyphenols are also present. Each of these vitamins is prevalent in many beauty products.

  • Alleviate an earache
  • Some alternative medicine providers recommend olive oil as a natural remedy for earaches. Sufferers are advised to apply the olive oil to a cotton swab and gently massage the out portion of the ear cavity. This is supposed to alleviate some of the associated pain and loosen the earwax. Some individuals suggest heating the oil for added benefit.

  • Control hair frizz
  • Olive oil provides relief from damaged hair. Simply apply the oil to the hair, while the hair is wet. Allow the oil to remain on the hair for 30 minutes. Rinse the oil from the hair. Enjoy the lustrous look and feel of the hair.

  • Bad sunburn
  • Individuals suffering from sunburn should to mix olive oil with white vinegar. Pour the mixture into a warm bath. The healing agents in olive oil sooth the skin and alleviate the burning sensation.

  • Dandruff problems
  • To alleviate symptoms associated with dandruff, mix olive oil with almond oil. Leave the product on the scalp for five minutes. Rinse the mixture from the hair to remove the dandruff. If the oil burns the scalp, rinse it immediately.

  • Shaving
  • Individuals who have sensitive skin may want to use olive oil as a shaving lubricant. The oils natural healing agents will soothe the skin.

  • Energy booster
    • Cure Diaper Rash
    • Hair Tonic
    • Personal Lubricant
    • Soothe a Sore Throat
    • Treat Lice
    • Remove Makeup or Paint from the Skin
    • Soothe Ulcers
    • Exfoliate Hands and Face
    • Moisturize Cuticles
  • Olive oil or oleuropein help to ward off fungi and yeast accumulation. Both of these may contribute to fatigue and lethargy. Individuals who consume oil on a daily basis have more energy to function.

    Other ailments that are alleviated by olive oil are as follows:

Forms of Oleuropein

Olive leaf is available to the consumer in a variety of forms. Oleuropein may be consumed by the individuals from olive leaf, olive leaf extracts, or fresh-picked leaf extracts in the following forms:

  • Liquid Concentrate
  • Dried Leaf Tea
  • Powder
  • Capsule

Consumers may choose to select the form based upon the type that is easiest for them to consume. Alternatively, the form may be selected based upon the amount of time it takes for the drug to be consumed into the blood stream.

What Oleuropein is Proven to do

Olive leaf contains oleuropein. One of the active ingredients in oleuropein is polyphenol. Polyphenols are helpful in finding free radicals and eliminating them to prevent disease. Several studies demonstrate the efficacy of olive leaf in the prevention of LDL cholesterol. The extract works by inhibiting LDL oxidation.
Side Effects of Oleuropein
High LDL levels are linked to the formation of atherosclerotic plaques. These plaques contribute to the formation of coronary heart disease. Active ingredients in the olive leaf have also prevented metal ion chelation and perioxidative chain reactions.

These two processes have been cited by scientists as playing a role in the development of heart disease and cancer. Olive leaf may also be beneficial in inhibiting enzymes that contribute to the inflammatory process, as well as, platelet aggregation, and inhibition of procarcinogen activation.

Though people who consume olive oil on a regular basis benefit from its health ramifications, there is no conclusive data indicating each of the benefits of oleuropein. Studies are being conducted with rodent subjects to determine the results conclusively. Each of the components of olive leaf, oleuropein, tyrosol, polyphenols and others must be studied separately in order to determine the efficacy of each component.

Typical Dosage and Usage Requirements

Since no research has been conducted to establish the necessity of oleuropein in a person’s daily diet, the Food and Drug Administration does not establish a Recommended Daily Allowance (RDA) with this particular supplement. More studies must be conducted to prove the efficacy of the supplement in an individual’s daily diet.

Individuals who desire to begin a regimen including olive leaf or oleuropein should follow the instruction of a physician or the label on the bottle. In general, however, individuals are recommended to take between 1 and 3 capsules with meals daily. Alternatively, if the person is ill, they should consume 1 capsule every 4 and 6 hours.

The pure form of oleuropein is combined with the inactive ingredients listed below to form a capsule:

  • Glycerin
  • Silicon Dioxide
  • Magnesium Stearate
  • Vegetable Cellulose

The product typically remains fresh and consumable for 2 years. Most forms originate from the Olea Europaea Olive Leaf Tree and stem. The leaves are gathered annually. The oil is extracted through a hydroenthanolic process. The capsule form of oleuropein contains no yeast, corn, wheat, gluten, soy, milk, preservatives or colors.

Regional Legal Status

This particular supplement is widely used within the Mediterranean diet and has been proven safe for consumption. There are no known regions that restrict the use of this particular supplement in the diet. Therefore, it is safe to consume oleuropein in any region of the country.

Potential Side Effects

Individuals with low blood pressure and diabetes may suffer even lower blood pressure and blood glucose levels as a result of consumption of oleuropein. Oleuropein may also interact with other pharmaceutical drugs that are designed to lower blood pressure or regulate diabetes. The interaction could result in a dangerous situation. Those who experience symptoms such as headache, nausea, flu-like symptoms, fainting, dizziness, and other life threatening symptoms should consult a physician immediately.

Those who are pregnant should conduct their physician before use. Keep the physician informed of each medication that you are taking in order to avoid unpleasant interactions or side effects.

Where to Purchase Oleuropein

Oleuropein may be purchased in any health food store or online. The amounts and forms that oleuropein will vary from store to store, depending upon the availability. The dosage ranges from 150 milligrams to 700 milligrams of olive leaf or oleuropein. The number of capsules or tablets per bottle range from 30 to 120.

Some of the popular brands of Oleuropein or Olive Leaf include:

  • Physiologics
  • Nature’s Way Products
  • Nature’s Herbs
  • Pure Encapsulations
  • Karuna
  • Bio-Botanical Research
  • Phytopharmica
  • Priority One
  • Natrol
  • Olivenol
  • Only Natural
  • Pastore Formulations

The Cost of Oleuropein

The prices of these forms of oleuropein vary based upon the potency, the brand, the amount per bottle, the type, and the store. For example, a consumer may purchase a bottle of 150 mg capsules of olive leaf for approximately $10. The bottle may contain 60 caplets. Alternatively, a consumer may purchase a bottle of 500 mg capsules of olive leaf for a little over $60. The costs vary significantly based upon the aforementioned attributes. Consumers are advised to shop around and conduct research to determine the best price for this particular supplement.